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Low levels of BRCA1 protein in the brain linked to dementia

  Mutant forms of breast cancer factor 1 (BRCA1) are associated with breast and ovarian cancers but according to new findings, in the brain the normal BRCA1 gene product may also be linked to Alzheimer's disease. The results, published in Nature Communications, suggest that low levels of BRCA1 protein in the brain may contribute to dementia. The study was funded by the National Institutes of Health.  It's extremely interesting that one molecule can be critically involved in two apparently opposing conditions: cancer