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MBL ELISA Kit

MBL ELISA Kit

Product name:MBL ELISA Kit
Specification:96test
Description:
Mannan-binding lectin (MBL; also called mannose binding lectin or protein) is a multimeric carbohydrate-binding protein produced in the liver and secreted into the blood, where it constitutes an important element in innate immune defense against invading microorganisms. Its normally oligomerized forms are associated with specific serine proproteases (the MASPs) which are activated when MBL binds to microbial carbohydrate surfaces and in turn activate complement via the MBL or lectin pathway. The determination of MBL concentrations in serum may be useful for the elucidation of suspected immune defects and as a prognostic indicator alerting to the need for heightened therapeutic or prophylactic measures in immunosuppressed patients, including patients receiving cancer chemotherapy, and patients with cystic fibrosis, SLE or rheumatoid arthritis.

 

 

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